Teruel Lab

Systems Biology Of Cell Signaling & Differentiation

Technology

Lab Technology

Targeted mass spectrometry; live-cell fluorescence microscopy; high-throughput screening of chemical, RNAi and DNA construct libraries; and computational modeling are among the tools we use for research.


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QUANTITATIVE TARGETED PROTEOMICS

We are using Selective Reaction Mass Spectrometry to obtain quantitative protein profiles of signaling networks. Our lab has a Thermo TSQ Vantage triple-quadropole mass spectrometer with Proxeon NanoHPLC dedicated to this approach.


 

tech-single-cell-imaging

SINGLE-CELL IMAGING

We use live and fixed microscopy to understand the single-cell dynamics underlying cell decision processes


tech-scheme_model

MODELING

Static diagrams cannot capture the dynamic interactions of signaling networks. We use quantitative modeling to be able to make sense of networks in time and space.